Polk CLIA Kit for Mouse(Mus musculus) | EIAab.comPolk CLIA Kit for Mouse(Mus musculus)

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Polk (Gene name),

DNA polymerase kappa (Protein name ), POLK_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Polk(Dinb1);

Protein name:

DNA polymerase kappa;

Alternative:

DINB protein(DINP);

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Interacts with PCNA (By similarity). Interacts with REV1.

Function:

DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Depending on the context, it inserts the correct base, but causes frequent base transitions, transversions and frameshifts. Lacks 3'-5' proofreading exonuclease activity. Forms a Schiff base with 5'-deoxyribose phosphate at abasic sites, but does not have lyase activity.

Subcellular Location:

Nucleus Detected throughout the nucleus and at replication foci.

Protein Attributes:

Sequence length:

852

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

750:

800:

850:

852:

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

STRING:

10090.ENSMUSP00000022172

String:

Q9QUG2

SMR:

Q9QUG2

UniGene:

Mm.89926

Pfam:

PF00817

KEGG:

mmu:27015

Uniprot:

Q9QUG2

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ELISA Kit for Mouse DNA polymerase kappa

Cat.:

E12062h

Price:

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Manual:

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Packing:

96T

Range:

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ELISA Kit for Mouse DNA polymerase kappa

Cat.:

E12062m

Price:

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

Range:

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CLIA Kit for Mouse DNA polymerase kappa

Cat.:

U12062h

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Mouse DNA polymerase kappa

Cat.:

U12062m

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Mouse DNA polymerase kappa

Cat.:

P12062Rb-m

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse DNA polymerase kappa

Cat.:

P12062Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Mouse DNA polymerase kappa

Protein for Mouse DNA polymerase kappa

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Mutation enhancement by DINB1, a mammalian homologue of the Escherichia coli mutagenesis protein dinB."
Ogi T. , Kato T. Jr. , Kato R. , Ohmori H.
Genes Cells4:607-618(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);TISSUE SPECIFICITY
strain: BALB/c.
tissue: Testis.
2.

"Human and mouse homologs of Escherichia coli DinB (DNA polymerase IV), members of the UmuC/DinB superfamily."
Gerlach V.L. , Aravind L. , Gotway G. , Schultz R.A. , Koonin E.V. , Friedberg E.C.
Proc. Natl. Acad. Sci. U.S.A.96:11922-11927(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue: Testis.
3.

"Pol kappa protects mammalian cells against the lethal and mutagenic effects of benzo[a]pyrene."
Ogi T. , Shinkai Y. , Tanaka K. , Ohmori H.
Proc. Natl. Acad. Sci. U.S.A.99:15548-15553(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];FUNCTION
4.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2);VARIANTS GLY-544; ALA-550; GLN-606; SER-692; SER-710; ALA-736 AND GLU-747
strain: C3H/He.
tissue: Osteoblast.
5.

"Mouse Rev1 protein interacts with multiple DNA polymerases involved in translesion DNA synthesis."
Guo C. , Fischhaber P.L. , Luk-Paszyc M.J. , Masuda Y. , Zhou J. , Kamiya K. , Kisker C. , Friedberg E.C.
EMBO J.22:6621-6630(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH REV1

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